on July 11, 2025
Collagen is an important protein in the human body and is often mentioned in relation to food and supplements. But what exactly is collagen? And what do terms like type I, II or III, hydrolysis and source actually mean? In this blog, we dive into the facts and answer some of the most frequently Googled questions.
1. What is collagen?
Collagen is a structural protein found in connective tissues such as skin, bones, tendons, ligaments, cartilage, blood vessels and teeth. The word comes from the Greek “kólla,” meaning ‘glue.’ In the body, collagen forms long fibrils in a triple helix structure.
2. Types of collagen: I, II, III (and more)
There are at least 28 types of collagen, but the most commonly mentioned are:
- Type I: the most abundant (around 90%), found in skin, bones, tendons and ligaments.
- Type II: mainly found in cartilage.
- Type III: often found alongside type I, present in skin, muscles and blood vessels.
Other types like IV and V serve specific functions (such as in organs or the lens of the eye) but are less common in supplements.
3. Where does collagen come from?
Collagen is derived from animal sources:
- Bovine: from cow bones and hides
- Porcine: from pig skin
- Marine: from fish – for example skin, scales or bones
- Chicken: mostly for type II, from cartilage
Hydrolysis (enzymatic or chemical breakdown) splits long collagen chains into smaller peptides, making collagen powders and capsules more water-soluble.
4. Hydrolyzed vs Native collagen
Native collagen is intact and forms thick fibrils (like in gelatin). Hydrolyzed collagen is broken down into small peptides, also known as collagen peptides. This results in:
- Improved water solubility
- Smaller molecules, resulting in better solubility in water
5. Marine vs land animal collagen
Marine collagen comes from fish and primarily contains type I. It is known for having a smaller molecular size compared to bovine collagen.
Bovine collagen typically contains types I and III; chicken cartilage is a source of type II.
Information about potential differences in bioavailability often refers to molecular size, but no health claims may be made based on this.
6. Nutrients that support collagen production
Natural collagen production in the body is complex. It requires:
- Vitamin C: a cofactor for enzymes that modify collagen-building blocks.
- Zinc and copper: zinc assists collagenase enzymes; copper helps with cross-linking via lysyl oxidase.
A protein-rich diet, healthy lifestyle and protection from UV radiation may help maintain collagen levels.
7. How to choose a collagen product
Look for the following:
- Collagen type – I, II, III, or a combination
- Source – fish, cow, pig or chicken
- Form – hydrolyzed peptides or native collagen
- Product quality – transparent sourcing and purification
- Certifications – Non‑GMO, sustainable, allergen information
8. Frequently asked questions
1. Can collagen be plant-based?
There is no true plant-based collagen. Some supplements contain ingredients that may support the body’s natural collagen production, but they do not contain actual collagen.
2. Is there a best time to take collagen?
No official timing exists. The key is to take it regularly and follow the recommended intake.
3. How do you recognize quality collagen?
Look for:
- Clearly stated source and collagen type
- Laboratory testing (e.g. for heavy metals)
- Certifications (Non‑GMO, allergen-free)
4. Are there side effects?
Current sources describe collagen as generally safe. However, individuals with allergies (e.g. to fish) should read the label carefully.
9. Good to know
- Collagen peptides contain amino acids like glycine, proline and hydroxyproline – essential building blocks of collagen.
- Collagen’s triple helix structure contributes to its mechanical strength.
- Collagen is produced by fibroblasts in a multistep process with various co-factors.
10. Summary
Collagen is a structural protein with many types and sources. Supplements often contain hydrolyzed peptides of types I, II or III, sourced from fish, cow or chicken. Hydrolysis results in smaller, water-soluble molecules. Vitamin C, zinc and copper play roles in the body’s natural collagen process. When choosing a supplement, check the source, type, form, and product transparency.
11. What is the difference between collagen and gelatin?
Gelatin is a partially hydrolyzed form of collagen. When collagen is heated, for example from bones or animal skin, it turns into gelatin. Gelatin is often used in desserts like pudding or gummy candies. While both come from the same protein, they differ in structure and usage. Gelatin gels, while collagen peptides dissolve in cold water.
12. Collagen-rich foods
Collagen itself is mainly found in animal products like bone broth. However, you can also support your body’s natural collagen process by eating foods rich in protein, vitamin C (e.g. citrus fruits, bell peppers), zinc (nuts and seeds), and copper (organ meats, cocoa).
13. How is collagen produced for supplements?
To produce collagen supplements, connective tissue like hides, bones or cartilage is cleaned, heated, and then enzymatically or chemically hydrolyzed. The result is a powder or capsule containing collagen peptides. Some brands further purify and test their products for heavy metals or contaminants, depending on the source and quality standards.
14. FAQ – Continued
5. How long can I use collagen?
There is no official limit on collagen usage. Always follow the dosage on the label. If unsure about long-term use, consult a health professional.
6. Do all collagen products contain the same ingredients?
No. Some contain only type I, others combine types I and III, or include supporting nutrients like vitamin C. Always read the full ingredient list.
7. Is collagen suitable for everyone?
Collagen is animal-derived and not suitable for vegans. People with allergies to fish, beef or chicken should pay close attention to the source.
15. What doesn’t belong in a collagen product?
Avoid unnecessary additives like artificial flavors, sugars, or unclear ingredients. Clean formulas with a transparent ingredient list are generally more trustworthy. A quality brand will list the collagen source, type and any added nutrients on the label.
16. What happens to collagen as you age?
As you age, collagen synthesis gradually slows down. Studies suggest that this process begins around the age of 25. Lifestyle factors like sun exposure, smoking and diet may influence this. A healthy lifestyle that includes enough protein, vitamin C and minerals may help support your natural collagen balance.
17. Why clear labeling matters
A good collagen product lists the source, collagen type and whether it is hydrolyzed. It may also state whether the product is allergen-free (e.g. fish, beef). Transparency helps consumers make informed choices. Look for quality marks and independent testing that confirm the product meets safety standards.
Our collagen products contain Naticol® fish collagen
The scientific evidence consistently shows that daily intake of Naticol® fish collagen peptides positively affects skin hydration, elasticity, and wrinkle formation at dosages starting from 2.5 g. Higher dosages (5 g and 10 g) provide additional benefits in firmness and hydration.
Thanks to its high bioavailability and excellent tolerability, Naticol® is a safe and effective choice for consumers looking to support their skin, hair, and nails.
Our product lines Pure Marine Collagen and Beauty Blend Collagen combine Naticol® with carefully selected vitamins and minerals.
Questions?
Want to learn more about collagen or looking for clean, transparent products? Browse our full range of collagen supplements and be sure to read the label carefully. Questions? Get in touch — we’re happy to help!
